NWBRC projects

Projects & Outcomes:

Current projects:

Identifying research through Public and Patient Perspectives and Priorities: The 4Ps study

A Qualitative Patient focused Research study

Contact: study4p@hotmail.com

Clinical Lead: Cliona Kirwin UHSM

Project lead: George Boundouki (Phase 1) & Rebecca Wilson (Phase 2)

Aim: The primary aim of this study is to identify the public’s priorities for breast cancer research. The secondary aims are to study how the public’s priorities relate to clinicians’ and academics’ priorities and to provide a guide for future studies in breast cancer.

Background: The NWBTRC plans to determine the research priorities of the public (including potential, current and past patients) in breast cancer care. Using the outcomes of the BCC Gap Analysis as a framework, we shall compare the priorities identified by the analysis to those identified by the public. In addition, we shall explore other public-perceived priority areas that were not covered in the BCC Analysis. We will correlate these priorities with those of clinicians and non-clinical academic researchers. More importantly we shall use these findings to direct future collaborative research.

We aim to undertake in phase one a series of listening events to determine public-perceived research priorities in breast cancer. Women who have had breast cancer treatment and healthy non-cancer women will be invited to participate. Those who have been involved in the care of a loved one who has battled breast cancer would also be welcome to participate. (Domecq et al. 2014). We will then form a questionnaire (phase two) with the research priorities from this study, the BCC gap analysis and Surgical gap for patients, public, scientists and clinicians to prioritise.

Latest update: Manuscript with results of the listening events and comparison to BCC and surgical gap prepared for submission. Questionnaire at pilot stage.

Next steering committee Meeting: TBA

Association of Breast Surgery Grant awarded

Steering Committee: James Harvey (Consultant mentor & grant co-applicant), Julia Henderson (Consultant mentor & grant co-applicant), Ashley Topps (Registrar in breast surgery and grant co-applicant), George Boundouki (Registrar in breast surgery and Steering committee chair), Paula Duxbury (Psychologist), Gavin Daker-White (Qualitative research expert), Julie Wray (Patient representative), Laura Ballance (Core surgical trainee), Rajiv Dave (Registrar in breast surgery), Mustafa Khanbhai (Registrar in breast surgery), Kate Williams (Registrar in breast surgery)

Outcomes:

Abstract

A novel approach to obtaining funding for patient and public participation in research

Boundouki G, Dave R, Ballance L, Teasdale RL, Henderson J, Harvey JR, Kirwan CC. Eur J Surg Oncol EJSO 2016; 42(5): S28

Oral Presentation

Setting up a public involvement study. Boundouki G, Henderson J, Topps A, Khanbhai M, Dave R, Ballance L, Williams K, Harvey JR, Kirwan CC. Mammary Fold Academic & Research Study Day 2016

Non-traditional approach to obtaining funding for patient and public participation in research.  Boundouki G, Dave R, Ballance L, Teasdale RL, Henderson J, Harvey JR, Kirwan CC National Research Collaborative Meeting 2015

Poster Presentation

A novel approach to obtaining funding for patient and public participation in research

Boundouki G, Dave R, Ballance L, Teasdale RL, Henderson J, Harvey JR, Kirwan CC. Association of Breast Surgeons 2016

Funding patient and public participation in research: an alternative to traditional sources. Ballance L, Boundouki G, Dave R, Teasdale RL, Henderson J, Harvey JR, Kirwan CC. Associations of Surgeons in Training 2016

Return to Activities of Daily living

A National Questionnaire based research study

Lead Laura Ballance, Rebecca Wilson

Contact: adlsQ2017@gmail.com

Aim: The primary aim of this study is to identify the recovery time of patients having undergone breast cancer surgery (mastectomy +/- reconstruction) and the time taken to return to activities of daily living. A secondary aim is to identify any factors delaying recovery and their return to activities of daily living.

Background: Our knowledge of the role of inherited genetics in breast cancer is constantly advancing, with two of the most well researched genes being BRCA 1 and BRCA 2. These are used to determine risk and when risk reducing surgery is appropriate. The decision to undergo such an operation must be well informed. There is currently little research or data to provide patients with accurate details of post –operative recovery after surgery. Recovery time and associated morbidity are contributing factors to aid patient’s decision making when facing difficult decisions around Oncoplastic techniques and risk reducing surgery. Having this information will help with the decision making process for women in the future. It will also enable clinicians to give realistic recovery advice to women. This can only be done if we can give information on recovery time for specific techniques.

Outcomes: Grant application in progress.

Project open to recruitment at six centres.  

 

Projects under development:

The management of breast cancer after augmentation

Project lead: Ben Baker

Outcomes in patients declining surgery for the treatment of breast cancer

Project lead: Hibia Fatyer

Previous projects:

Implant Infection Prophylaxis Study:

Project lead:  Julia Henderson

Steering committee: Sandhir Kandola, Susan Hignett, Rebecca Teasdale, Ashley Topps, Cliona C Kirwan

Background: Infective complications following breast-implant surgery are difficult to treat and can lead to explantation.  We aimed to establish current use of all infection-prophylaxis measures, specifically adherence to ABS Oncoplastic guidelines for MRSA, MSSA screening and prophylactic antibiotics and to assess application of other infection-control precautions.

Outcomes: 

Publications

Infection Prophylaxis for Breast Implant Surgery: Could We Do Better? J, Henderson on behalf of the North West Breast Surgical Research Collaborative. ePlasty June 2017;  Volume: 17; ID: e19; ISSN: 1937-5719

Abstracts

Covert surveillance of infection prophylaxis measures applied during implant surgery Henderson J, Kandola S, Hignett S, Teasdale R, Topps A, Kirwan CC. Eur J Surg Oncol EJSO 2015; 41(6): S60.

Poster presentations

Covert surveillance of infection prophylaxis measures applied during implant surgery

Julia R Henderson  on behalf of the North West Breast Trainees Research Collaborative Association of breast surgery 2015

 

Explant of implant-based breast reconstruction study:

Project leads: Matt Rowland, Sandhir Kandola

Outcomes: 

Oral presentations

Expanding the scope of implant based reconstruction; good results can be achieved in challenging and high-risk patients – Matthew P Rowland, Sandhir K Kandola, Rebecca L Teasdale, James R Harvey, Julia R Henderson, David M Riding, Cliona C Kirwan. Oncoplastic & Reconstructive Breast Surgery 2015

Outcomes for Dermal Sling reconstruction may be superior to those using Acellular Dermal Matrix in a multi-centre cohort – Matthew P Rowland, Rebecca L Teasdale, Sandhir K Kandola, Cliona C kirwan.  Julia R Henderson, Kate Williams & James R Harvey” Oncoplastic & Reconstructive Breast Surgery 2015

Poster presentations

Expanding the scope of implant based reconstruction; good results can be achieved in challenging and high-risk patients – Matthew P Rowland, Sandhir K Kandola, Rebecca L Teasdale, James R Harvey, Julia R Henderson, David M Riding, Cliona C Kirwan              San Antonio Breast Cancer Symposia 2015

Infection prevention in breast implant surgery – A review of the surgical evidence, guidelines and a checklist

Infection prevention in breast implant surgery

Steering group : S.P. Barr, A.R. Topps , N.L.P. Barnes , J. Henderson , S. Hignett , R.L. Teasdale , A. McKenna , J.R. Harvey , C.C. Kirwan

Outcomes:

Publications

Infection prevention in breast implant surgery – A review of the surgical evidence, guidelines and a checklist

S.P. Barr, A.R. Topps , N.L.P. Barnes , J. Henderson , S. Hignett , R.L. Teasdale , A. McKenna , J.R. Harvey , C.C. Kirwan On behalf of the Northwest Breast Surgical Research Collaborative. European Journal of Surgical Oncology , Volume 42 , Issue 5 , 591 – 603

Abstracts

Infection Prevention in Breast Implant Surgery – A Novel Intraoperative Checklist and Review of the Evidence. Barr SP, Topps AR, Barnes NLP, Henderson J, Hignett S, Teasdale RL, McKenna A, Harvey JR, Kirwan CC. Eur J Surg Oncol EJSO 2016; 42(5): S50

Oral Presentations

Surgical Site Infection and Implant-Based Breast Reconstruction – A Review of the Evidence. Barr SP, Topps AR, Barnes NLP, Henderson J, Hignett S, Teasdale RL, McKenna A, Harvey JR, Kirwan CC. iBRA2 Study Day 2015

Infection Prevention in Breast Implant Surgery – A Review of the Surgical Evidence, Guidelines and a Checklist. Barr SP, Topps AR, Barnes NLP, Henderson J, Hignett S, Teasdale RL, McKenna A, Harvey JR, Kirwan CC. Mammary Fold Academic & Research Study Day 2016

Poster presentations

Infection Prevention and Breast Implant Surgery – A Review of the Surgical Evidence and Guidelines. Barr SP, Topps AR, Barnes NLP, Henderson J, Hignett S, Teasdale RL, McKenna A, Harvey JR, Kirwan CC. National Research Collaborative Meeting 2015

Infection Prevention in Breast Implant Surgery – A Novel Intraoperative Checklist and Review of the Evidence. Barr SP, Topps AR, Barnes NLP, Henderson J, Hignett S, Teasdale RL, McKenna A, Harvey JR, Kirwan CC. Association of Breast Surgeons 2016

 

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